Bridge Funding Program All Recipients

Summer 2019
 
Wen Li, Chemistry
Exploiting Non-equilibrium Charge Dynamics in Polyatomic Molecules to Steer Chemical Reactions
 
December 2018
 
Izabela Podgorski, Pharmacology
Functional Role of Bone Marrow Adipocytes in Metastatic Prostate Cancer
 
Timothy Stemmler, Pharmaceutical Sciences
Structural Insights into the Function of Fataxin
 
August 2018
 
Linda Hazlett, Ophthalmology
Killing Multi-Drug Resistant Pseudomonas aeruginosa

Anna Moszczynska, Pharmaceutical Science
The role of E3 ligase parkin in vulnerability to develop methamphetamine addiction
 
April 2018
 
Alan Dombkowski, Pediatrics
The role of non-coding RNAs in epilepsy of tuberous sclerosis complex and focal cortical dysplasia type 2B
 
December 2017
 
Bonnie Sloane, Pharmacology
Tissue-engineered cancer avatars: An integrated predictive system for malignant progression and treatment response
 
July 2017
 
Michael Bannon, Pharmacology
Long Noncoding RNAN in Opioid Abuse
 
Mark Cheng, Electrical and Computer Engineering
Smart contact lenses for wireless diagnosis of infectious keratitis using transparent graphene bioelectronics
 
Stephan Patrick, Oncology
Novel Mechanism of APOBEC3 Cytidine Deaminase Activation of BER in Mediating Cisplatin Efficacy
 
Malathy Shekhar, Oncology
Delineating a novel mechanism of endocrine resistance in breast cancer
 
March 2017
 
Aloke Dutta, Pharmaceutical Sciences
Novel Neuroprotective Treatment for Parkinson's Disease
 
Lori Pile, Biological Sciences
Role of Histone Deacetylation in Cell Cycle Progression and Development
 
November 2016
 
Ashok Bhagwat, Chemistry
Mapping uracils in mammalian genomes
 
Zhixian Zhou, Physics and Astronomy
Novel electronics and physics based on 2D atomic semiconductors
 
July 2016
 
None
 
March 2016
 
Randall Armant, Obstetrics and Gynecology
Noninvasive Investigation of Placental and Fetal Viability
 
Jin Cha, Chemistry
Organic Synthesis Based on Cyclopropanols
 
Gilda Hillman, Oncology
Soy Modulation of Inflammatory Responses Induced by Lung
 
Tomomi Ichinose, Anatomy and Cell Biology
Modulation of Visual Processing in Retina Bipolar Cells by Dopamine
 
NOVEMBER 2015

Bruce Berkowitz, Ophthalmology
Novel Imaging of Rod Oxidative Stress in Disease and Treatment in Vivo
 
David Kessel, Pharmacology
Sensitizing Malignant Cells to Apoptotic Death by Lysosomal Photodamage
 
 JULY 2015

Maik Huttemann, Center for Molecular Medicine and Genetics
Regulation of Respiration and Apoptosis by Cytochrome c Phosphorylation
 
Hyeong-Reh Choi Kim, Pathology
PDGF D and Prostate Cancer Bone Metastasis
 
Victoria Meller, Biological Sciences
Small RNA and Whole Chromosome Recognition in Drosophila Melanogaster
 
Jeffrey Potoff, Chemical Engineering
Development of a High Performance, Parallel Gibbs Ensemble Monte Carlo Simulation Engine
 
MARCH 2015

Jeffrey Withey, Immunology
Vibrio Cholerae Pathogenesis in Humans and Fish

NOVEMBER 2014

Randall Armant, Obstetrics and Gynecology
Assessment of Human Placentas in Real Time
 
Xiaoyan Han, Electrical and Computer Engineering
Bridge Funding on Sonic Infrared Imaging Non-destructive Evaluation of Advanced Composite Materials
 
Henry Heng, Center for Molecular Medicine and Genetics
Linking Genomic Instability and ER Stress to Gulf War Illness
 
JULY 2014

Christine Chow, Chemistry
The Role of Ribosomal RNA Modifications
 
David Cinabro, Physics and Astronomy
R&D on CCD's for Astronomy at Lawrence Berkely National Lab
 
Tamara Hendrickson, Chemistry
Ammonia Transport through a Hydrophilic Ammonia Tunnel
 
MARCH 2014
 
Patrick Mueller, Physiology
Inactivity and Enhanced Sympathoexcitation: Role of Neuroplasticity in the RVLM
 
Zhengping Yi, Pharmaceutical Sciences
Human Skeletal Muscle Proteome and Phosphoproteome in Obesity and Type 2 Diabetes
Ammonia Transport through a Hydrophilic Ammonia Tunnel
 
Ho-Sheng Lin, Otolaryngology
Identification of Early Marker for Head and Neck Cancer through Antibody Profiling
 
Philip Pellett, Immunology and Microbiology
Biogenesis and Operation of the Human Cytomegalovirus Assembly Complex
 
JULY 2013

Q Ping Dou, Oncology
Bortezomib Resistance and AMPK Signaling in Multiple Myeloma
 
Tamara Hendrickson, Chemistry
Ammonia Transport through a Hydrophilic Ammonia Tunnel
 
Kenneth Hohn, Pathology
12-HETER1, a High-affinity Receptor or 12(S)-Hydroxyeicosatetraenoic Acid in Prostate Carcinoma
 
Mahendra Kavdia, Biomedical Engineering
Nitric Oxide-Superoxide Interactions in Endothelial Cell Dysfunction
 
Anjan Kowluru, Pharmaceutical Sciences
Protein Prenyltransferases in Glucose-Stimulated Insulin Secretion
 
Ho-Sheng Lin, Otolaryngology
Identification of Early Marker for Head & Neck Cancer through Antibody Profiling
 
Enrique Ostrea, Pediatrics
Prevention of Pesticide and Lead Exposures in Mothers and their Children
 
Takeshi Sakamoto, Physics and Astronomy
Direct Imaging of Cooperative Movement of the Non-processive Motor, Myosin 5c
 
Malathy Shekhar, Oncology
Evaluation of Rad6 Small Molecule Inhibitor
 
MARCH 2013
 
Robert Akins, Biochemistry and Molecular Biology
Validation of a rapid tool for diagnosing and predicting bacterial vaginosis
 
Xiaoyan Han, Electrical and Computer Engineering
Sonic Infrared Imaging Non-destructive Evaluation of Advanced Composite Materials
 
Sandra Jacobson and Joseph Jacobson, Psychiatry and Behavioral Neurosciences
Etiology and Prevention of Fetal Alcohol Spectrum Disorders in Cape Town, South Africa
 
Menq-Jer Lee, Pathology
Lipid Signaling in Adipose Inflammation and Vascular Dysfunction
 
Li Li, Internal Medicine
The Role of SM22 in the Pathogenesis of Aortic Aneurysms
 
Jeffrey Taub, Pediatrics and Yubin Ge, Oncology
Molecular and Pharmacologic Correlates of Acute Myeloid Leukemia in Down Syndrome
 
Gen Sheng Wu, Oncology
Developing Targeted Therapeutics for Triple-negative Breast Cancer
 
NOVEMBER 2012

Donald DeGracia, Physiology
Ribonomics and Brain Ischemia
 
Miriam Greenberg, Biological Sciences
The Role of Cardiolipin in the TCA Cycle – Implications for Barth Syndrome
 
Susil Putatunda, Chemical Engineering
Development of Nanostructured Austempered Ductile Iron (ADI)
 
Assia Shisheva, Physiology
Functions of Adipocyte PIKfyve and its Lipid Products
 
JULY 2012

Karen Beningo, Biological Sciences
Calpains and Mechanical Forces
 
David Gorski, Surgery
Glutamatergic Signaling as a Therapeutic Target for Breast Cancer
 
Peter Hoffmann, Physics and Astronomy
Nanomechanics and Dynamics of Confined Water Layers
 
Nathan McCaughtry, Kinesiology
Detroit Healthy Youth Initiative
 
Takeshi Sakamoto, Physics and Astronomy
The Structure and Function of Actin Bundle Protein TRIOBP
 
Christopher Steiner, Biological Sciences
The Impacts of Dispersal and Clonal Diversity on the Stability of Environmentally-forced Metacommunities
 
MARCH 2012

Sandro da Rocha, Chemical Engineering
Nanocarriers for the Delivery of siRNA to the Lungs
 
Chunying Li, Biochemistry and Molecular Biology
EPC Homing and Angiogenesis: a Role of CXCR2 Macromolecular Complex
 
Li Li, Internal Medicine
Genetic Control of Smooth Muscle Inflammation in Response to Vascular Injury
 
Philip Pellett, Immunology and Microbiology
Biogenesis and Operation of the Human Cytomegalovirus Assembly Complex
 
John Reiners, Institute of Environmental Health Sciences
Targeting Insulin-like Growth Factor-1 Receptor as a Therapy for NF1 Malignant Peripheral Nerve Sheath Tumors
 
Youming Xie, Oncology
Proteasomal Degradation of Rpn4
 
NOVEMBER 2011

David Randall Armant, Obstetrics and Gynecology
Defects in Mitochondria Impacting Primate Oocyte Quality
 
Nabanita S. Datta, Internal Medicine/Endocrinology
Role of MAP Kinase Phosphatase-1 in the Anabolic Actions of PTH in Osteoblasts
 
Venuprasad K. Poojary, Oncology
Ubiquitination in the Regulation of Inflammation and Cancer
 
JULY 2011

Ikuko Kato, Oncology and Pathology
Luminal Bacterial Markers and Colorectal Cancer Risk
 
Nicholas Davis, Pharmacology
Protein Palmitoylation in Yeast and Mammals
 
Kenneth Honn, Pathology
Role of GPR31, a High-affinity Receptor of 12(S)-HETE, in Prostate Cancer Progress

Tiffany Mathews, Chemistry
The Interplay between Ethanol, Dopamine, and BDNF
 
Gen Sheng Wu, Oncology
The Mechanisms of TRAIL Resistance in Cancer Cells
 
Guojun Wu, Oncology and Pathology
Forkhead-Box Q1 in Breast Cancer Metastasis and Chemoresistance
 
MARCH 2011

Robert Akins, Biochemistry and Molecular Biology
Development and Validation of New PCR Tools for Human Vaginal Microbiome Analysis
 
Sandra Jacobson, Psychiatry and Behavioral Neuroscience
Exploratory Trial of Choline Supplementation for Fetal Alcohol Syndrome
 
Youming Xie, Oncology
Proteasomal Degradation of Rpn4
 
Alexander Gow, Center for Molecular Medicine and Genetics
Trb3-Mediated Modulation of Oligodendrocyte Stress
 
Tamara Hendrickson, Chemistry
Substrate Divergence in Aminoacyl-tRNA Biosynthesis
 
Sharon Ackerman, Biochemistry and Molecular Biology
Biophysics of Neurofilament Compaction: The Hallmark of Traumatic Axonal Injury
 
Ashis Mukhopadhyay, Physics and Astronomy
Nanoscale Dynamics of Confined Fluids by Time-Correlated Fluorescence Spectroscopy within an Atomic Force Microscope.
 
NOVEMBER 2010

Andrew Feig, Chemistry
Investigations of RNA-Hfq Interactions
 
Russell Finley, Center for Molecular Medicine and Genetics
Defining Genetic Networks Required for Cell Division and Viability
 
Leonard Lipovich, Center for Molecular Medicine and Genetics
Differential Expression and Regulatory Functions of Long Non-coding RNA Molecules in the Nucleus Accumbens of Human Cocaine and Heroin Abusers
 
Raymond Mattingly, Pharmacology
Regulation of Ras through the Ras-GRF Exchange Factor
 
Lori Pile, Biological Sciences
Role of Histone Deacetylation in Cell Cycle Progression and Development
 
Jeffrey Withey, Immunology and Microbiology
Mechanisms for Control of Vibrio cholerae Virulence
 
JULY 2010

Bhanu Jena, Physiology
Chemistry of Calcium-Lipid Interactions: Implication in Life Processes
 
Jianjun Wang, Biochemistry and Molecular Biology
Structural Studies of apoE and its Interaction with LDL Receptors
 
John Cavanaugh, Biomedical Engineering
Prevention of Blast-Related Injuries
 
David Oupicky, Pharmaceutical Sciences
Gene Delivery Modulated by Redox Potential Gradients
 
Malathy Shekhar, Pathology, Karmanos Cancer Institute
Delineating the Origin of Triple Negative Basal-like Breast Cancer
 
MARCH 2010

Gen Sheng Wu, Pathology
Role and Regulation of the Phosphatase CL100/MKP1 in Human Cancer
 
Melody Neely, Immunology and Microbiology
Analysis of the Virulence Mechanism of a lantibiotic Locus
 
Sean Wu, Mechanical Engineering
Path to Intelligent Noise Control
 
Gyula Acsadi, Pediatrics, Neurology
Inherited Neuropathy Consortium: An integrative Approach Leading to Therapy
George Borszcz, Psychology
Emotion of Pain: A Neurobiological Analysis
 
Tamara Hendrickson, Chemistry
GPI Anchor Attachment: Substrate Specificity and Tumorigenicity
 
Hasan Jamil, Computer Science
Automatic Tools for the Integration and Analysis of Life Sciences Data
 
NOVEMBER 2009

Lore Pile, Biology
Role of Histone Deacetylation in Cell Cycle Progression and Development
 
Sandra Jacobson, Psychiatry and Behavioral Neurosciences
Choline Supplementations for Fetal Alcohol Syndrome Prevention in Cape Town, South Africa
 
Todd Leff, Pathology
Regulation of skeletal muscle metabolism by PPAR-gamma
 
Bonnie Sloane, Pharmacology
Cathepsins in Malignant Progression
 
Andrew Feig, Chemistry
Investigations of Hfq-RNA Interactions and Related RNA Chaperones
 
JULY 2009

Louis Romano, Chemistry
Effect of DNA Adducts on dNTP Binding to E. coli DNA Polymerase I
 
Judith Whittum-Hudson, Immunology and Microbiology
Biodegradable Nanoparticles for Targeted Antibiotic Delivery
 
Wen Li, Mechanical Engineering
SBIR Phase I: Non-invasive vibro-acoustic diagnostic and prognostic system
 
MARCH 2009

Gyula Acsadi, Pediatrics
The Effects of SMN Depletion on the Expression of Genes Participating in Axonal Growth and Transport
 
Mary Ann Kosir, Surgery
Targeting Breast Cancer Metastasis: Role of Chemokine Heparanase
 
Mark VanBerkum, Biology
Signal Transduction Mechanisms Regulating Axon Guidance of Drosophila Pioneer Neurons
 
Michael Cher, Urology
Proteases in Prostate Cancer Bone Metastasis
 
NOVEMBER 2008

David Evans, Biochemistry
Control of Pyrimidine Biosynthesis in Mammalian Cells
 
Hyeong-Reh Kim, Pathology
PDGF-regulation of Cell Growth and Death

Melody Neely, Immunology and Microbiology
Analysis of the Virulence Mechanism of a lantibiotic Locus
 
Abhilash Pandya, Electrical and Computer Engineering
Real-time Augmented Reality Development and Human Factors Assessment for the Special Purpose Dexterous manipulator
 
Jeffrey Stanley, Psychiatry
Spectroscopy and MRI in ADHD
 
Gen Sheng Wu, Karmanos Cancer Institute
Role and Regulation of the Phosphatase CL100/MKP1 in Human Cancer
 
JULY 2008

Robert Akins, Biochemistry
Molecular Diagnostics of Pathogenic Fungi
 
Scott Bowen, Psychology
Self-Administration of Abused Inhalants in Mice
 
Dennis Drescher, Otolaryngology
Identification of Acoustico-Lateralis Transmitters
 
Miriam Greenberg, Biological Sciences
A Novel Mechanism of Regulation of Inositol Biosynthesis in Yeast
 
Ananda Prasad, Internal Medicine
Deficiency and Th1 Functions: Molecular Mechanisms
 
Judith Whittum-Hudson, Immunology and Microbiology
Pathogenic Mechanisms in Chlamydial Reactive Arthritis
 
Hai-Young Wu, Pharmacology
Genome Organization: Coordinated Gene Expression
 
MARCH 2008

Michael Cher, Urology
Proteases in Prostate Cancer Bone Metastasis
 
Robert MacKenzie, Psychiatry and Behavioral Neurosciences
CREB Regulation of Gene Expression in NPY/AgRP Hypothalamic Neurons
 
Mairi Noverr, Immunology and Microbiology
The Role of Oxylipins in the Development of Pulmonary Allergy
 
Anders Sima, Pathology
The Effects of Various Modes of Administration of C-peptide on Diabetic Neuropathy
 
Yong Xu, Electrical and Computer Engineering
Novel Single Molecule DNA Sequencing Method
 
Albert King, Biomedical Engineering
 
NOVEMBER 2007

Husam Abu-Soud, Obstetrics and Gynecology
Regulation of Myeloperoxidase Catalysis by Nitric Oxide and Ascorbate
 
Xiaoyan Han, Electrical & Computer Engineering
IR Crack Detection in Aircraft Structures Using Chaotic Sound Excitation
 
Daniel Rappolee, Obstetrics and Gynecology
Effects of microgravity on Preimplantation Mouse Development
 
Melissa Runge-Morris, Institute of Environmental Health Sciences
Sulfotransferase Expression: Implications for Toxicity
 
JULY 2007

George Brush, Pathology
Mechanism of Mec1p in the Checkpoint Response
 
John Cavanaugh, Biomedical Engineering
Neurophysiology of Whiplash Pain
 
David Evans, Biochemistry and Molecular Biology
Control of Pyrimidine Biosynthesis in Mammalian Cells
 
Rafael Fridman, Pathology
Novel Nanoprobe Approach to Investigate Membrane Proteases in Live Cancer Cells
 
S. Helena Kuivaniemi, Surgery
Genetic Risk Factors in Abdominal Aortic Aneurysms
 
Leslie Lundahl, Psychiatry and Behavioral Neurosciences
Cue Reactivity Model for Assessing Pharmacologic Intervention in Treatment of Cannabis Use Disorders
 
Ananda Prasad, Hematology-Oncology
Zinc Deficiency and Th1 functions: Molecular Mechanisms
 
Thipparthi Reddy, Immunology and Microbiology
Small Heat Shock Proteins as Novel HIV-1 Therapeutic Agents
 
Gabriel Sosne, Anatomy and Cell Biology
 
Chin-An Tan, Mechanical Engineering
Collaborative Research: A Novel Video-Assisted Integrated Approach for Enhancing Bridge Health Monitoring
 
Guri Tzivion, Pathology
Regulation of c-Raf-1 by Ras and Growth Factors
 
Fayth Yoshimura, Immunology and Microbiology
DNA Forms of Murine Leukemia Viruses
 
MARCH 2007

Donald DeGracia, Physiology
The Unfolded Protein Response After Brain Ischemia
 
Robert Freedman, Psychiatry and Behavioral Neurosciences
Behavioral Treatment of Menopausal Hot Flashes
 
Sandra Jacobson, Neurology
Identification of FASD in South African Children
 
Jason Mateika, Physiology
Respiratory Chemoreflex Control in Obstructive Sleep Apnea
 
Boris Nadgorny, Physics and Astronomy
The Development of the Multifunctional Scanning Nanoprobe and its Application to the New Spintronics Materials Development
 
Melody Neely, Immunology and Microbiology
Streptococcal-Zebrafish Model of Bacterial Pathogenesis
 
Daniel Rappolee, Obstetrics and Gynecology, Anatomy and Cell Biology
Impact of Stress and Stress Enzymes on Peri-implantation Embryonic Development
 
Jeffrey Taub, Pediatrics
GATA1, Chromosome 21 and Chemotherapy Sensitivity
 
NOVEMBER 2006
 
Miriam Greenberg, Biological Sciences
Synthetic Lethal Interactions in Barth Syndrome
 
Enrique Ostrea, Pediatrics Fetal Exposure to Environmental Toxins and Infant Outcome

Bonnie Sloane, Pharmacology
Validation of Proteases as Therapeutic Targets in Breast Cancer: Functional Imaging of Protease Expression, Activity, and Inhibition
 
Melissa Runge-Morris, Institute of Environmental Health Sciences
 
JULY 2006

Stephanie Brock, Chemistry
Transition Metal Pnictides Nanoparticles: Synthesis, Assembly and Patterning of Novel Magnetic Materials
 
Li Li, Internal Medicine
Genetic Control of Smooth Muscle Gene Expression
 
Andrea Sankar, Anthropology
Living with HIV and Adhering to Treatment through Time
 
Malathy Shekhar, Pathology, Karmanos Cancer Institute
 
Shijie Sheng, Pathology
A Role of Maspin in Human Prostate Tumor Progression