Bloodborne Pathogens in Research

The Michigan Occupational Safety & Health Administration (MIOSHA) Bloodborne Infectious Diseases Standard applies to all workers who may be exposed to human blood, body fluids, tissue, or other potentially infectious materials as part of their job duties.

See the WSU Bloodborne Infectious Diseases Exposure Control Plan for our written policy to comply with the MIOSHA Standard.

Use of human materials in research

Research involving the use of human cell lines, tissue, blood, and/or other potentially infectious material is handled at Biosafety Level 2 (BSL-2). While this research does not require IBC review and approval, workers and laboratories must still meet the MIOSHA requirements.

Human cell lines

BSL-2 is appropriate for activities with: all primate cell lines, even well established ones, all cells derived from primate lymphoid or tumor tissues; all primate tissue; all human clinical material*; cultured cells new to the laboratory until proven contaminant-free; and, cells exposed to or transformed by a primate oncogenic virus.

*These activities and the use of any cells purposely infected with or suspected of harboring agents defined as bloodborne pathogens are covered by the Occupational Safety & Health Administration (OSHA) Bloodborne Pathogens Standard. Laboratories using human cell strains (non-transformed cells) propagated from primary explants must also comply with the Standard because they are considered "unfixed human tissue" which is covered by the regulation.

Additional information: